Indication

Hypertension, Diabetic nephropathy,

Adult Dose

Oral Hypertension Adult: Initial: 10-20 mg once daily may then be increased up to max 40 mg once daily if needed. Elderly: No dosage adjustment nee... View More

Child Dose

Oral Hypertension Child: 6-16 yr <35 kg: 10 mg once daily; dosage range: 10-20 mg/day >35 kg: 20 mg once daily. Doses may be doubled once if necessa... View More

Renal Dose

Renal impairment: Mild to moderate (CrCl: 20-60 mL/min): Max: 20 mg once daily.

Contraindication

Pregnancy (2nd and 3rd trimesters); biliary obstruction.

Mode of Action

Olmesartan is a selective and competitive angiotensin II Type 1 (AT1) receptor antagonist that blocks the vasoconstrictor and aldosterone-secreting effe... View More

Precaution

Drugs that act on renin-angiotensin system can cause fetal injury and death when used in 2nd and 3rd trimesters of pregnancy. Olmesartan medoxomil shoul... View More

Side Effect

1-10% Dizziness,Headache,Fatigue,Diarrhea,Hyperglycemia,Hypertriglyceridemia,Back pain,Bronchitis,Inflicted injury,Flulike symptoms,Pharyngitis,Rhiniti... View More

Pregnancy Category Note

Pregnancy category: 1st trimester, C; 2nd and 3rd trimesters, D

Interaction

Increased risk of hyperkalaemia w/ ACE inhibitors, K-sparing diuretics, K salts or K supplements and drugs that may increase serum