Generic

Ciclesonide

Indications

Ciclesonide nasal spray is used to treat the symptoms of seasonal allergic rhinitis in people over the age of six and perennial allergic rhinitis in people over the age of twelve.

Pharmacology

Ciclesonide is a corticosteroid that has anti-inflammatory properties. It's a ciclesonide aqueous suspension for topical application to the nasal mucosa using a metering and atomizing spray pump. Before using the pump for the first time or after a long period of inactivity, it must be primed (4 days or more).

Dosage

1 spray (50 micrograms/spray) in each nostril once a day. The maximum total daily dosage should not exceed 2 sprays in each nostril (200 micrograms/day).

Priming information: Gently shake the bottle and prime Ciclesonide nasal spray by actuating eight times before using for the first time or when not used for 4 consecutive days.

Administration

How to use the Nasal Spray-

• Shake the bottle gently and remove the dust cover.
• Hold the spray with your forefinger and middle finger on either side of the nozzle and your thumb underneath the bottle. Press down until a fine spray appears. If using for the first time or if you have not used it for a week or more, press the nasal applicator several times until a fine moist comes out from the container.
• Gently blow the nose to clear the nostrils.
• Close one nostril and carefully insert the nasal applicator into the open nostril. Tilt your head forward slightly and keep the spray upright. Breathe in through your nose and while breathing in, press the white-collar of nasal applicator firmly down once to release a spray.
• Breathe out through your mouth.
• Repeat the above steps in the same/ other nostril for consecutive doses.

Cleaning: The nasal spray should be cleaned at least once a week. The procedures are as follows-

• Remove the dust cover.
• Gently pull off the nasal applicator.
• Wash the applicator and dust cover in warm water.
• Shake off the excess water and leave to dry in a normal place. Avoid to apply additional heat.
• Gently push the applicator back on the top of the bottle and re-fix the dust cover.

Side Effects

Ciclesonide nasal spray is absorbed less into rest of the body; therefore fewer side effects are seen. However, few side-effects like headache, dizziness, nosebleed, stuffy nose, earache may occur.

Pregnancy & Lactation

Category C pregnancy. Only if the possible benefit outweighs the potential risk to the fetus should Ciclesonide nasal spray be used during pregnancy. Ciclesonide is not known to be excreted in human milk. Other corticosteroids are excreted in human milk, thus caution should be given when giving them to nursing mothers.

Precautions & Warnings

In patients with active or quiescent tuberculosis of the respiratory tract, untreated fungal, bacterial, or systemic viral infections, or ocular herpes simplex, Ciclesonide nasal spray should be used with caution. Intranasal application has been linked to rare cases of nasal septal perforation, cataract, and glaucoma. Candida albicans infections of the nose and throat have only been reported on a few occasions. Although systemic effects of Ciclesonide nasal spray have been low at approved doses, the risk of side effects increases with higher doses. Ciclesonide nasal spray in doses more than those indicated should be avoided.

Therapeutic Class

Respiratory corticosteroids

Storage Conditions

Store at a temperature of no more than 25 degrees Celsius. Light and dampness should be avoided. Keep out of children's reach.

Pharmaceutical Name

Incepta Pharmaceuticals Ltd.