Indication

Hypertension, Congestive heart failure, Oedema, Ascites

Adult Dose

Adult: Per tab contains furosemide 20 mg and spironolactone 50 mg. 1-4 tabs/day.

Contraindication

Hypersensitivity, anuria or severe oliguria, hypovolaemia, hyponatraemia, hypotension, urinary retention due to prostatic hypertrophy, Addison's disease... View More

Mode of Action

Furosemide inhibits reabsorption of Na+, Cl- and K+. Continuous use may also lead to secondary hyperaldosteronism. Spironolactone is a specific antagoni... View More

Precaution

Concomitant use with ACE inhibitors, monitor fluids and electrolytes including changes in serum K levels. Dilutional hyponatraemia or even a true low-sa... View More

Side Effect

Fluid and electrolyte imbalance, nausea, diarrhoea, blurred vision, headache, dizziness, hypotension, photosensitisation, hepatic dysfunction, hyperglyc... View More

Interaction

1. Frusemide: Aminoglycosides and ethacrynic acid (increased ototoxicity), tubocurazine, succinylcholine (effects enhanced). Sucralfate reduces effects ... View More