Introduction

Meropen 1gm is an antibiotic that fights bacteria. It is used to treat severe infections of the skin, lungs, stomach, urinary tract, blood and brain (eg... View More

Uses of Meropen 1gm

• Severe bacterial infections

Side effects of Meropen 1gm

• Injection site reactions (pain, swelling, redness)
• Nausea
• Vomiting
• Headache
• Rash

How to use Meropen 1gm

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Meropen 1gm works

Meropen 1gm is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them t... View More

What if you forget to take Meropen 1gm?

If you miss a dose of Meropen 1gm, please consult your doctor.

Indication

Cystic fibrosis, Intra-abdominal infections, Meningitis, Skin and skin structure infections, Diabetic foot infection

Administration

IV Administration Administer IV infusion over 15-30 minutes; administer IV bolus over 3-5 minutes

Adult Dose

Intravenous Intra-abdominal infections Adult: 1 g 8 hrly via IV inj over approx 3-5 min or infused over approx 15-30 min. Skin and skin structure i... View More

Child Dose

Children: IV 60 mg/kg/day, max 3 g/day q8h 120 mg/kg/day meningitis, max 6 g/day q8h Intravenous Intra-abdominal infections Child: >3mth ?50 kg:... View More

Renal Dose

Renal impairment: CrCl (ml/min) 26-50 Usual dose 12 hrly. 10-25 Half the usual dose 12 hrly. <10 Half the usual dose 24 hrly.

Contraindication

Hypersensitivity to meropenem, other carbapenems. History of anaphylactic reaction to β-lactams (e.g. penicillins, cephalosporins).

Mode of Action

Meropenem is a synthetic carbapenem beta-lactam antibiotic that exerts its bactericidal activity by inhibiting bacterial cell wall synthesis in gm+ve an... View More

Precaution

Patient w/ underlying CNS disorders (e.g. brain lesions, history of seizures. Not recommended for treatment of MRSA. Renal impairment. Childn. Pregnancy... View More

Side Effect

1-10% Constipation (1-7%),Diarrhea (4-5%),Nausea or vomiting (1-4%),Rash (2-3%; includes diaper-area moniliasis in pediatric patients),Headache (2%),In... View More

Interaction

Increased plasma concentration w/ probenecid. May decrease plasma levels of valproic acid thus, increasing the risk of seizures