Indication

B1, B6 and B12 deficiency syndrome, sciatica, lumbago, trigeminal neuralgia, facial paralysis, optic neuritis, Diabetic neuropathy, Peripheral neuralgia, Myalgia

Adult Dose

Adult Tablet: 1-2 tablets three times daily. Injection: Intramuscular In severe cases, 1 inj daily until the acute symptoms subsides. For milder cases, & follow up therapy 2 or 3 injections should be administered weekly.

Contraindication

Should not be used in the patients on Levodopa therapy and hypersensitivity to any of the active ingredients.

Mode of Action

Vitamin B1 (Thiamine), B6 (Pyridoxine) & B12 (Cyanocobalamin). These vitamins play essential role as co-enzyme for the metabolism of nervous system. Thus this combination normalizes the nerve cell metabolism. This combination supports the regeneration of nerve fibers and myelin sheath by activation of the metabolism and the natural repair mechanism. The combination of these 3 vitamins shows better efficacy than that of the individual components. In addition, Vitamin B1, B6 & B12 promote body's own repair mechanism and work in pain management.

Precaution

Cyanocobalamin should not be given before a diagnosis has been fully established because of the possibility of masking symptoms of subacute degeneration of the spinal cord. Cyanocobalamin is not a suitable form of Vitamin B12 for the treatment of optic neuropathies associated with raised plasma concentrations of cyanocobalamin.

Side Effect

Generally well tolerated. However, a few allergic reactions may be seen.